Why This Job is Featured on The SaaS Jobs
Clinical-stage life sciences companies increasingly operate with SaaS-like expectations around data integrity, cross-functional operating cadence, and distributed collaboration. This Senior Medical Director role sits at the center of that operating model, translating clinical evidence into decisions that shape a program’s trajectory while coordinating inputs from clinical operations, biometrics, regulatory, and commercial stakeholders. The remit spans trial design through execution and interpretation, making it a pivotal node in how evidence is generated and communicated.
For a SaaS career lens, the durable value here is systems thinking in a regulated environment. Leading medical monitoring, aligning teams on strategy, and producing core clinical and regulatory narratives builds a repeatable skill set around governance, stakeholder management, and decision-making under uncertainty. Experience interpreting safety and efficacy signals, and turning them into clear guidance for internal and external partners, is highly transferable to productized, platform-oriented organizations where outcomes depend on disciplined processes and high-quality documentation.
This role best suits professionals who prefer ownership over a defined therapeutic program and who are comfortable operating through influence rather than direct authority. It will fit someone who enjoys synthesizing complex data into practical direction, maintaining rigorous standards, and working effectively with external investigators, CROs, and internal teams in a remote or hybrid setup.
The section above is editorial commentary from The SaaS Jobs, provided to help SaaS professionals understand the role in a broader industry context.
Job Description
Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company developing cell therapies for patients suffering from autoimmune diseases. Guided by our core values, Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation and help redefine what’s possible.
Title: Sr. Medical Director, Clinical Development
Location: Remote or Hybrid
Reports To: SVP, Clinical Development & Medical Affairs
Responsibilities
Serve as the physician lead for CAR T-cell therapy clinical trials in autoimmune disease indications, in partnership with internal and external cross-functional teams. Oversee medical monitoring of clinical trials, including engagement with site investigators and external medical monitors. Partner with clinical operations, biometrics, regulatory, and commercial teams to ensure alignment on strategy and execution. Lead design, execution, and interpretation of clinical trials across assigned program Provide medical and scientific input into clinical development plans, study protocols, investigator brochures, and regulatory submissions. Medical review, analysis, and interpretation of safety, efficacy, and PK and biomarker data. Development of clinical trial documents including protocols, ICFs, clinical development plans, and publications. Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities. Actively engage with external investigators and researchers to identify, evaluate, and support investigator sponsored studies and drive research collaborations.
Qualifications
MD, DO, (or ex-US equivalent) or MD-PhD degree required. 7+ years of clinical research experience with 4+ years of industry experience in late phase clinical development involved in the design and execution of clinical trials. Experience in late-stage clinical development preferred. Specialty training in neurology, rheumatology, nephrology and/or industry experience in clinical development of cell therapies and/or therapies for autoimmune diseases is highly preferred. Proven ability to interpret, discuss and present efficacy and safety data. Strong knowledge of GCP/ICH, clinical trial design, clinical development processes, and regulatory requirements. Strong ability to communicate and establish effective working relationship with investigators, collaborators, scientific advisors, CROs, and corporate partners.
The salary range for this position is from $330,000 to 370,000 USD annually. This salary range is an estimate of what we reasonably expect to pay for this posted position, and the actual salary may vary based on various factors, including without limitation individual education, experience, tenure, skills and abilities, as well as internal equity and alignment with market data. This position is also eligible for bonus, benefits, and participation in Company’s stock plan.
